Acid-base / renal
Anion gap (with albumin correction)Acid-base / renal · based on Emmett M and Narins RG (1977) · 4 inputsCalculated serum osmolalityAcid-base / renal · based on Dorwart WV and Chalmers L (1975) · 5 inputsCreatinine clearance (Cockcroft–Gault)Acid-base / renal · based on Cockcroft DW and Gault MH (1976) · 4 inputsCreatinine clearance from a timed urine collectionAcid-base / renal · based on Cockcroft DW and Gault MH (1976) · 4 inputseGFR — CKD-EPI 2021 race-free (creatinine; creatinine–cystatin C)Acid-base / renal · based on Inker LA et al. (2021) · 4 inputsExpected serum sodium change from infusate and urine outputAcid-base / renal · based on Adrogué HJ and Madias NE (2000) · 9 inputsFractional excretion of sodium (FENa)Acid-base / renal · based on Espinel CH (1976) · 4 inputsFree water deficit in hypernatremiaAcid-base / renal · based on Yun G et al. (2023) · 3 inputsInfusate rate for a target sodium change (Adrogué–Madias)Acid-base / renal · based on Adrogué HJ and Madias NE (2000) · 6 inputsKinetic eGFR (creatinine changing acutely)Acid-base / renal · based on Chen S (2013) · 6 inputsOsmolal gapAcid-base / renal · based on Purssell RA et al. (2001) · 6 inputsResidual renal urea clearance (Kru) in hemodialysisAcid-base / renal · based on National Kidney Foundation (2015) · 5 inputsSodium corrected for hyperglycemiaAcid-base / renal · based on Katz MA (1973) · 2 inputsSodium deficit (hyponatremia)Acid-base / renal · based on Adrogué HJ and Madias NE (2000) · 4 inputs
Body measurements
Body mass index (BMI)Body measurements · published 2000 · 2 inputsBody surface areaBody measurements · based on Mosteller RD (1987) · 2 inputsIdeal, lean and adjusted body weightBody measurements · based on Janmahasatian S et al. (2005) · 3 inputsLean body mass from urinary creatinine excretionBody measurements · based on Forbes GB and Bruining GJ (1976) · 1 input
Cardiac
AHA PREVENT equations — 10- and 30-year risk of total CVD, ASCVD and heart failure (2023)Cardiac · based on Khan SS et al. (2024) · 14 inputsAortic Dissection Detection Risk Score (ADD-RS) with D-dimer (ADvISED)Cardiac · based on Isselbacher EM et al. (2022) · 13 inputsCardiac output by the Fick principleCardiac · based on Nunn JF (1993) · 7 inputsCHA2DS2-VASc (atrial fibrillation stroke risk)Cardiac · based on Lip GY et al. (2010) · 7 inputsCorrected QT interval (QTc)Cardiac · based on Bazett HC (1920) · 2 inputsHAS-BLED (bleeding risk on anticoagulation in AF)Cardiac · based on Pisters R et al. (2010) · 9 inputsHEART score for chest pain in the emergency departmentCardiac · based on Six AJ et al. (2008) · 5 inputsIntracranial hemorrhage risk with thrombolysis for MI in older adults (Brass)Cardiac · based on Brass LM et al. (2000) · 8 inputsPooled Cohort Equations — 10-year ASCVD risk (ACC/AHA 2013)Cardiac · based on Goff DC Jr et al. (2013) · 9 inputsPulmonary vascular resistanceCardiac · based on Humbert M et al. (2022) · 3 inputsRevised Jones criteria for acute rheumatic fever (AHA 2015)Cardiac · based on Gewitz MH et al. (2015) · 11 inputsSan Francisco Syncope RuleCardiac · based on Quinn JV et al. (2004) · 5 inputsTIMI risk score — STEMICardiac · based on Morrow DA et al. (2000) · 8 inputsTIMI risk score — UA / NSTEMICardiac · based on Antman EM et al. (2000) · 7 inputsCHADS2 (atrial fibrillation stroke risk)Cardiac · based on Gage BF et al. (2001) · 5 inputsSuperseded → CHA2DS2-VASc (atrial fibrillation stroke risk)Framingham 10-year coronary heart disease risk (Wilson 1998 point score)Cardiac · published 1998 · 9 inputsSuperseded → Pooled Cohort Equations — 10-year ASCVD risk (ACC/AHA 2013)Framingham 10-year general cardiovascular disease risk (D'Agostino 2008)Cardiac · based on D'Agostino RB Sr et al. (2008) · 8 inputsSuperseded → Pooled Cohort Equations — 10-year ASCVD risk (ACC/AHA 2013)Framingham 5-year stroke risk in new-onset atrial fibrillation (Wang)Cardiac · based on Wang TJ et al. (2003) · 5 inputsSuperseded → CHA2DS2-VASc (atrial fibrillation stroke risk)Framingham 5-year stroke-or-death risk in new-onset atrial fibrillation (Wang)Cardiac · based on Wang TJ et al. (2003) · 7 inputsSuperseded → CHA2DS2-VASc (atrial fibrillation stroke risk)Jones criteria for acute rheumatic fever (1992 update)Cardiac · published 1992 · 11 inputsSuperseded → Revised Jones criteria for acute rheumatic fever (AHA 2015)SPAF thromboembolism risk in atrial fibrillation (1992)Cardiac · published 1992 · 3 inputsSuperseded → CHA2DS2-VASc (atrial fibrillation stroke risk)
Cardiovascular
Critical care
ABC score (Assessment of Blood Consumption) for massive transfusion in traumaCritical care · based on Nunez TC et al. (2009) · 4 inputsAPACHE II severity scoreCritical care · based on Knaus WA et al. (1985) · 17 inputsMultiple Organ Dysfunction Score (MODS, Marshall)Critical care · based on Marshall JC et al. (1995) · 8 inputsqSOFA (quick SOFA) — Sepsis-3 bedside promptCritical care · based on Singer M et al. (2016) · 3 inputsShock index (heart rate ÷ systolic blood pressure)Critical care · based on Rossaint R et al. (2023) · 2 inputsSIRS criteria (systemic inflammatory response syndrome)Counts the four 1992 ACCP/SCCM SIRS criteria (temperature, heart rate, respiratory rate or PaCO2, white cell count or bands); 2 or more meets SIRS. Sepsis-3 now defines sepsis by organ dysfunction instead.SOFA score (Sequential [Sepsis-related] Organ Failure Assessment)Critical care · based on Vincent JL et al. (1996) · 9 inputs
Critical care / anesthesia
Arterial oxygen content (CaO2)Critical care / anesthesia · based on Nunn JF (1993) · 3 inputsEstimated blood volume and allowable blood lossCritical care / anesthesia · based on Gross JB (1983) · 4 inputsOxygen consumption (VO2) from expired gasCritical care / anesthesia · based on Nunn JF (1993) · 3 inputsVenous oxygen content (CvO2)Critical care / anesthesia · based on Nunn JF (1993) · 3 inputs
Electrolytes
Endocrine
A1c ↔ estimated average glucose (ADAG)Endocrine · based on Nathan DM et al. (2008) · 2 inputsCambridge diabetes risk score — probability of undiagnosed type 2 diabetes (Griffin)Endocrine · based on Griffin SJ et al. (2000) · 7 inputsMetabolic syndrome (harmonized 2009; AHA/NHLBI 2005 cut-offs)Endocrine · based on Alberti KG et al. (2009) · 5 inputsA1c ↔ mean plasma glucose (Rohlfing / DCCT)Endocrine · published 2002 · 2 inputsSuperseded → A1c ↔ estimated average glucose (ADAG)
Gastroenterology
Gastrointestinal
Irritable bowel syndrome — Rome IV criteria and subtypeGastrointestinal · based on Mearin F et al. (2016) · 7 inputsOakland score — safe discharge after lower GI bleedingGastrointestinal · based on Oakland K et al. (2017) · 7 inputsStrate rule — severe acute lower intestinal bleedingGastrointestinal · based on Strate LL et al. (2003) · 7 inputsIrritable bowel syndrome criteria (pre-Rome IV)Gastrointestinal · published 1990 · 6 inputsSuperseded → Irritable bowel syndrome — Rome IV criteria and subtype
Geriatrics
Hematology
Hematology / VTE
Caprini VTE risk score (surgical patients)Adds Caprini risk-factor points for venous thromboembolism in surgical patients and gives the ACCP 2012 risk category (very low, low, moderate, high) with the estimated baseline VTE risk without prophylaxis.Padua Prediction Score (VTE risk in hospitalized medical patients)Adds 11 weighted risk factors to identify hospitalized medical patients at high risk of venous thromboembolism (4 or more points) who may benefit from thromboprophylaxis.
Hematology/Oncology
MDS Revised International Prognostic Scoring System (IPSS-R)Hematology/Oncology · based on Greenberg PL et al. (2012) · 5 inputsMultiple myeloma, smoldering myeloma and MGUS (IMWG 2014)Hematology/Oncology · based on Rajkumar SV et al. (2014) · 11 inputsMDS International Prognostic Scoring System (IPSS, 1997)Hematology/Oncology · based on Greenberg P et al. (1997) · 3 inputsSuperseded → MDS Revised International Prognostic Scoring System (IPSS-R)Multiple myeloma diagnostic criteria (Durie-era)Hematology/Oncology · based on Durie BG and Salmon SE (1975) · 8 inputsSuperseded → Multiple myeloma, smoldering myeloma and MGUS (IMWG 2014)
Hepatology
MELD 3.0Hepatology · based on Kim WR et al. (2021) · 7 inputsPELD-Cr score (OPTN 2023 pediatric end-stage liver disease, with creatinine)Hepatology · published 2025 · 7 inputsMELD (original, 2002 UNOS)Hepatology · based on Kamath PS et al. (2001) · 4 inputsSuperseded → MELD 3.0PELD score (2002 formula) — pediatric end-stage liver diseaseHepatology · published 2002 · 6 inputsSuperseded → PELD-Cr score (OPTN 2023 pediatric end-stage liver disease, with creatinine)
Infectious disease
2023 Duke-ISCVID criteria for infective endocarditisInfectious disease · based on Fowler VG et al. (2023) · 12 inputsMcIsaac (modified Centor) score for streptococcal pharyngitisInfectious disease · based on McIsaac WJ et al. (1998) · 5 inputsDuke criteria for infective endocarditis (1994, with the 2000 "possible" definition)Infectious disease · based on Durack DT et al. (1994) · 8 inputsSuperseded → 2023 Duke-ISCVID criteria for infective endocarditisStreptococcal pharyngitis prediction in children (Attia)Infectious disease · based on Attia MW et al. (2001) · 4 inputsSuperseded → McIsaac (modified Centor) score for streptococcal pharyngitis
Laboratory
Musculoskeletal
FRACTURE Index with BMD (Black) — 5-year fracture riskMusculoskeletal · based on Black DM et al. (2001) · 7 inputsOsteoporosis risk SCORE (Lydick) — who needs bone densitometryMusculoskeletal · based on Lydick E et al. (1998) · 6 inputsOsteoporosis Self-assessment Tool (OST)Musculoskeletal · based on Koh LK et al. (2001) · 3 inputs
Neonatology
Newborn hyperbilirubinemia — AAP 2022 phototherapy, escalation-of-care and exchange thresholds (≥ 35 weeks)Neonatology · based on Kemper AR et al. (2022) · 4 inputsNewborn hyperbilirubinemia — Bhutani risk zone and AAP 2004 thresholds (≥ 35 weeks)Neonatology · based on Bhutani VK et al. (1999) · 3 inputsSuperseded → Newborn hyperbilirubinemia — AAP 2022 phototherapy, escalation-of-care and exchange thresholds (≥ 35 weeks)
Neurology
Neurology / infectious
Neurology / trauma
ABCD² score (stroke risk after TIA)Neurology / trauma · based on Johnston SC et al. (2007) · 5 inputsCanadian CT Head Rule (minor head injury, adults)Neurology / trauma · based on Stiell IG et al. (2001) · 7 inputsGlasgow Coma ScaleNeurology / trauma · based on Teasdale G and Jennett B (1974) · 3 inputsNIH Stroke Scale (NIHSS)Neurology / trauma · based on Brott T et al. (1989) · 15 inputsTIA prognosis — 90-day stroke risk (California score, Johnston 2000)Neurology / trauma · based on Johnston SC et al. (2000) · 5 inputsSuperseded → ABCD² score (stroke risk after TIA)
Obstetrics
Bishop score (cervical favourability for induction of labour)Scores dilation, effacement or cervical length, station, consistency and position (0–13) to judge whether the cervix is favourable before induction of labour; NICE uses 6 or less vs more than 6 to choose the method.Due date and gestational age (from LMP or EDD)Obstetrics · published 2017 · 3 inputsGestational age from crown–rump length (Robinson)Obstetrics · based on Robinson HP and Fleming JE (1975) · 1 inputShould the due date be changed? (LMP vs ultrasound, ACOG)Obstetrics · published 2017 · 2 inputs
Oncology
Pediatrics
Apgar scorePediatrics · based on Apgar V (1953) · 5 inputsBacterial Meningitis Score (children)Pediatrics · based on Nigrovic LE et al. (2002) · 5 inputsCDC growth percentiles, 2–20 years (BMI, stature, weight for age)Pediatrics · based on Kuczmarski RJ et al. (2000) · 5 inputsCDC weight-for-stature percentile (77–121 cm)Pediatrics · based on Kuczmarski RJ et al. (2000) · 3 inputsKawasaki disease — complete and incomplete criteria (AHA 2017)Pediatrics · based on McCrindle BW et al. (2017) · 15 inputsMaintenance fluid rate (Holliday–Segar, 4-2-1)Pediatrics · based on Holliday MA and Segar WE (1957) · 1 inputPECARN head injury rule — children aged 2 years and olderPediatrics · based on Kuppermann N et al. (2009) · 6 inputsPECARN head injury rule — children younger than 2 yearsPediatrics · based on Kuppermann N et al. (2009) · 6 inputsPediatric Appendicitis Score (Samuel)Pediatrics · based on Samuel M (2002) · 8 inputsWHO growth standards, birth to 24 months (weight, length, head circumference, weight-for-length)Pediatrics · published 2006 · 6 inputsCDC infant growth percentiles, 0–36 monthsPediatrics · based on Kuczmarski RJ et al. (2000) · 5 inputsSuperseded → WHO growth standards, birth to 24 months (weight, length, head circumference, weight-for-length)
Perioperative
Postoperative pneumonia risk index (Arozullah)Perioperative · published 2001 · 14 inputsRevised Cardiac Risk Index (Lee)Perioperative · based on Lee TH et al. (1999) · 6 inputsDetsky modified cardiac risk index (1986)Perioperative · based on Detsky AS et al. (1986) · 10 inputsSuperseded → Revised Cardiac Risk Index (Lee)Goldman cardiac risk index (1977)Perioperative · based on Goldman L et al. (1977) · 9 inputsSuperseded → Revised Cardiac Risk Index (Lee)
Prognosis
Psychiatry
Pulmonary
Alveolar–arterial (A–a) oxygen gradientPulmonary · based on Mellemgaard K (1966) · 7 inputsBODE index for COPDPulmonary · based on Celli BR et al. (2004) · 4 inputsBrock University (PanCan) model — probability that a screen-detected lung nodule is cancerPulmonary · based on McWilliams A et al. (2013) · 10 inputsCURB-65 pneumonia severityPulmonary · based on Lim WS et al. (2003) · 5 inputsPeak expiratory flow variabilityPulmonary · based on Global Initiative for Asthma (2024) · 2 inputsPneumonia Severity Index (PSI / PORT)Pulmonary · based on Fine MJ et al. (1997) · 20 inputsPredicted peak expiratory flow (adults)Pulmonary · based on Nunn AJ and Gregg I (1989) · 4 inputsSolitary pulmonary nodule malignancy probability (Mayo Clinic model)Pulmonary · based on Swensen SJ et al. (1997) · 6 inputsCURB (pneumonia severity, without age)Pulmonary · based on Lim WS et al. (2003) · 4 inputsSuperseded → CURB-65 pneumonia severity
Rheumatology
Statistics
Toxicology
Trauma / burns
Trauma / orthopedics
Canadian C-Spine Rule (alert, stable adult trauma)Trauma / orthopedics · based on Stiell IG et al. (2001) · 9 inputsNEXUS low-risk criteria for cervical-spine imagingTrauma / orthopedics · based on Hoffman JR et al. (2000) · 5 inputsOttawa ankle ruleTrauma / orthopedics · based on Stiell IG et al. (1993) · 4 inputsOttawa foot ruleTrauma / orthopedics · based on Stiell IG et al. (1993) · 4 inputsOttawa knee ruleTrauma / orthopedics · based on Stiell IG et al. (1996) · 5 inputs
Venous thromboembolism
Age-adjusted D-dimer cut-off for suspected PEVenous thromboembolism · based on Righini M et al. (2014) · 2 inputsPulmonary embolism rule-out criteria (PERC)Venous thromboembolism · based on Kline JA et al. (2004) · 9 inputsSimplified Pulmonary Embolism Severity Index (sPESI)Venous thromboembolism · based on Jiménez D et al. (2010) · 6 inputsWells score for DVT (2003 modified)Venous thromboembolism · based on Wells PS et al. (2003) · 10 inputsWells score for pulmonary embolismVenous thromboembolism · based on Wells PS et al. (2000) · 7 inputsKuijer bleeding risk on anticoagulation for VTE (1999)Venous thromboembolism · based on Kuijer PM et al. (1999) · 3 inputsSuperseded → HAS-BLED (bleeding risk on anticoagulation in AF)Outpatient Bleeding Risk Index (Beyth 1998)Venous thromboembolism · based on Beyth RJ et al. (1998) · 4 inputsSuperseded → HAS-BLED (bleeding risk on anticoagulation in AF)
Dosing utilities
Adult dose scaled to body surface areaDosing utilities · based on Du Bois D and Du Bois EF (1916) · 3 inputsBSA-based doseDosing utilities · based on Mosteller RD (1987) · 4 inputsCarboplatin dose (Calvert formula)Dosing utilities · based on Calvert AH et al. (1989) · 6 inputsCorticosteroid dose equivalence (glucocorticoid effect)Dosing utilities · based on Liu D et al. (2013) · 3 inputsIV infusion rate from a weight-based doseDosing utilities · 4 inputsTotal iron deficit (Ganzoni)Dosing utilities · based on Ganzoni AM (1970) · 3 inputsWeight-based dose and liquid volumeDosing utilities · 4 inputs
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Decision support for clinicians — review before acting. These calculators do not diagnose or decide. They are offered, never run automatically, and the treating clinician decides what a score means for the patient in front of them. Partners can call the same calculators through the Pogosh CDS API.