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SIRS criteria (systemic inflammatory response syndrome)

Current versionCritical care·6 inputs·2 references

Counts the four 1992 ACCP/SCCM SIRS criteria (temperature, heart rate, respiratory rate or PaCO2, white cell count or bands); 2 or more meets SIRS. Sepsis-3 now defines sepsis by organ dysfunction instead..

Pogosh offers this calculator when a case matches pneumonia, pyelonephritis, uti, cellulitis, meningitis, septic shock. It runs only when you press Calculate.

Decision support for clinicians — review before acting.

°C
/min
/min
mmHg
×10³/µL
%
Runs only when you press Calculate. Values are not stored.

References

  1. Bone RC, Balk RA, Cerra FB, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. Chest. 1992;101:1644-1655. PMID 1303622. PubMed 1303622
  2. Singer M, Deutschman CS, Seymour CW, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016;315:801-810. PMID 26903338; PMC4968574 (Box 1). PubMed 26903338
Implementation notes

Thresholds are strict inequalities as printed, so 38.0 °C, 90/min, 20/min and 12,000/mm³ exactly do not count. WBC is entered in ×10³/µL (12 = 12,000/mm³). PaCO2 and band count are optional, and when absent they cannot add a criterion. Related calculators: qSOFA and SOFA.

Related calculators

APACHE II severity scoreMultiple Organ Dysfunction Score (MODS, Marshall)ABC score (Assessment of Blood Consumption) for massive transfusion in traumaShock index (heart rate ÷ systolic blood pressure)qSOFA (quick SOFA) — Sepsis-3 bedside promptSOFA score (Sequential [Sepsis-related] Organ Failure Assessment)

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